|
Post by timholycross on Nov 12, 2020 14:23:33 GMT -5
A pox on Cuomo if he blocks distribution for other than scientific reasons.
|
|
|
Post by sader1970 on Nov 12, 2020 14:35:37 GMT -5
I obviously missed something important if there was something reported that Cuomo wants to block vaccines from being distributed once they've been approved as medically safe and effective.
|
|
|
Post by rgs318 on Nov 12, 2020 14:43:35 GMT -5
I am in the same boat.
|
|
|
Post by hchoops on Nov 12, 2020 17:01:55 GMT -5
A pox on Cuomo if he blocks distribution for other than scientific reasons. What would give you any idea that he would do such a thing ?
|
|
|
Post by KY Crusader 75 on Nov 12, 2020 17:16:48 GMT -5
Insanity
For clarification-I believe it would be insane to block distribution of the vaccine for political reasons
|
|
|
Post by Pakachoag Phreek on Nov 12, 2020 17:26:45 GMT -5
I obviously missed something important if there was something reported that Cuomo wants to block vaccines from being distributed once they've been approved as medically safe and effective. Before the election, Cuomo and Gov. Newsom both said their states would independently assess the safety and efficacy of a vaccine. This was said at a time when 'promises' were being voiced about a vaccine being ready in late October. As it was, the timeline was such that a vaccine would/could not be available by that date, because all vaccine candidates must complete a two month period to determine safety. The two month period begins after all participants in the trial are vaccinated. This did not occur until around the end of September. Pfizer has said that the test of efficacy of its vaccine, compared to placebo, accelerated in recent weeks because of the major uptick in infections. IMO, Pfizer's vaccine will have a limited geographic distribution. This is because it must be stored and transported at -94F. One of Pfizer's big production facilities is in Andover MA, so MA citizens may benefit by being proximate to the production source. Moderna's vaccine, which is likely to have an efficacy similar to Pfizer's, need only be stored at several degrees below 0F. (I can't remember the precise value, it is single digits.) Moderna's main plant is in Norwood MA. It has another plant in NH. Pfizer's largest facility is in Kalamazoo MI. Its third vaccine production facility is in St. Louis.
|
|
|
Post by Pakachoag Phreek on Nov 12, 2020 17:59:00 GMT -5
I drafted this the other day after watching a video clip of Fauci's CNN interview with Blitzer. ______________________________________________________ Not only the light at the end of the tunnel, but the end of the tunnel.
Based on Fauci’s mid-week interview with Wolf Blitzer. No more “cautious optimism” on Fauci’s part. He flat-out declared that the U.S. will have at least two vaccines by the end of the year. Pfizer’s and Moderna’s.
Fauci, in February, was hopeful there would be one vaccine approved by beginning of 2021.
He expects vaccinations to start probably mid-late December.
Both Pfizer’s and Moderna’s vaccines are based on the same messenger RNA approach. This approach has never been used before for a vaccine. Both require two shots, 3-4 weeks apart. Both require cold storage and transport, Pfizer’s stored at -94F, Moderna’s at -4F.
Fauci had been hoping for a vaccine efficacy rate of 70-75 percent. He called Pfizer’s efficacy rate of more than 90 percent “Extraordinary.” He hinted he expected to see a similar efficacy rate from Moderna’s vaccine, because of the underlying technology. Fauci and his NIAID closely monitor Moderna’s trial progress, as the government is funding the development. Pfizer self-financed its vaccine development, so NIAID staff had less visibility.
Moderna will have 20 million doses by year’s end, enough for 10 million individuals. Pfizer will have 50 million doses globally by end of December, enough for 25 million individuals. Both will be producing many hundreds of millions of doses in 2021.
Vaccination priorities: health care workers, first responders, residents of congregate care facilities (nursing homes). - -- - - - -- - - Treatment: FDA approved Eli Lilly’s monoclonal antibody treatment, bamlanivimab, for COVID. This is similar to Regeneron. Trump received Regeneron. Apparently, Governor Christie and Dr. Ben Carson received/receiving Lilly’s antibody treatment. Lilly will produce 800,000 doses in December; Regeneron will produce 300,000 doses by the end of that month. First-line treatment, administered early. Both monoclonal antibodies are administered by infusion, so would require a clinic or hospital setting.
|
|
|
Post by hcpride on Nov 12, 2020 18:33:00 GMT -5
/\ Two things: That (-94 Degrees Fahrenheit) is VERY cold if you ask me. AND there is a good deal of money involved: “In July, Pfizer got a $1.95 billion deal with the government’s Operation Warp Speed, the multiagency effort to rush a vaccine to market, to deliver 100 million doses of the vaccine. The arrangement is an advance-purchase agreement, meaning that the company won’t get paid until they deliver the vaccines. Pfizer did not accept federal funding to help develop or manufacture the vaccine, unlike front-runners Moderna and AstraZeneca.” www.nytimes.com/2020/11/10/health/was-the-pfizer-vaccine-part-of-the-governments-operation-warp-speed.html
|
|
|
Post by Pakachoag Phreek on Nov 12, 2020 19:56:02 GMT -5
|
|
|
Post by Pakachoag Phreek on Nov 14, 2020 6:36:37 GMT -5
Back to Cuomo. There was a dust-up yesterday between the President and Cuomo about when New York will receive vaccine shipments. www.foxnews.com/media/trump-remarks-vaccine-distribution-new-yorkCuomo went out on a limb in October, with some justification*, but now the President has taken a saw to the limb. My advice to the Governor is scramble back off that limb. *Cuomo feared that the Administration would direct the FDA to give an emergency use authorization to a vaccine in October,
|
|
|
Post by sader1970 on Nov 14, 2020 8:18:54 GMT -5
Yeah, a pissing match between Trump and Cuomo that millions of New Yorkers will get sprayed on. Phreek nailed it.
|
|
|
Post by hcpride on Nov 14, 2020 9:29:01 GMT -5
Back to Cuomo. There was a dust-up yesterday between the President and Cuomo about when New York will receive vaccine shipments. www.foxnews.com/media/trump-remarks-vaccine-distribution-new-yorkCuomo went out on a limb in October, with some justification*, but now the President has taken a saw to the limb. My advice to the Governor is scramble back off that limb. *Cuomo feared that the Administration would direct the FDA to give an emergency use authorization to a vaccine in October, It was not October, it was Cuomo's (Monday) November 9 "Good Morning America" commentary that precipitated the current dust-up. As noted in the cited article. In any case, nothing is coming of it.
|
|
|
Post by longsuffering on Nov 14, 2020 19:51:18 GMT -5
Cuomo vs Trump: Alpha Male on Alpha Male crime.
|
|
|
Post by Pakachoag Phreek on Nov 16, 2020 7:21:08 GMT -5
|
|
|
Post by Pakachoag Phreek on Nov 16, 2020 7:29:50 GMT -5
|
|
|
Post by matunuck on Nov 16, 2020 9:31:35 GMT -5
Nevertheless, the results of the JNJ vaccine, in particular, will be very helpful if the company comes in with good enough number and shows that it also reduces the severity of those who contract COVID. JNJ vaccine is a single shot (though they are also tracking the results of a second shot booster with a separate study group) and will be easier to distribute to more remote areas of the world with limited resources. We will see.
|
|
|
Post by alum on Nov 16, 2020 9:43:49 GMT -5
Dr. Fauci suggested very early this year that it would take12 to 18 months from start to finish to get a vaccine. It looks like he nailed it. Once approved, they will start distributing it to health care workers, first responders, nursing home employees and residents, people who work in manufacturing of vaccines, prison employees and inmates, farm workers living in congregate housing, meat packing plant employees and eventually the rest of us.
(Obviously, I have missed other high risk and essential groups. These are just some that came right to mind. Maybe in the ACC college basketball players will be a priority, too.)
|
|
|
Post by ndgradbuthcfan on Nov 16, 2020 11:07:41 GMT -5
WH's supposed Corona expert, Dr. Scott Atlas, criticized Michigan Governor Whitmer's steps to control the virus and advised Michiganders' to "rise up" against her protocols (whatever that means). Dr. Fauci, it turn, stated that "he totally disagrees with the stand that he (Atlas) takes".
|
|
|
Post by Chu Chu on Nov 16, 2020 12:59:37 GMT -5
WH's supposed Corona expert, Dr. Scott Atlas, criticized Michigan Governor Whitmer's steps to control the virus and advised Michiganders' to "rise up" against her protocols (whatever that means). Dr. Fauci, it turn, stated that "he totally disagrees with the stand that he (Atlas) takes". During the 1918 Flu pandemic, there was no vaccine, and we went with the "herd immunity" paradigm similar to what is now advocated by Atlas. 50 million people died, at a time when the population of the United States was about 100 million. That, in a nutshell, is why it is so important to follow Dr. Fauci's advice now, until we have the vaccine available and in use.
|
|
|
Post by ndgradbuthcfan on Nov 16, 2020 13:19:30 GMT -5
WH's supposed Corona expert, Dr. Scott Atlas, criticized Michigan Governor Whitmer's steps to control the virus and advised Michiganders' to "rise up" against her protocols (whatever that means). Dr. Fauci, it turn, stated that "he totally disagrees with the stand that he (Atlas) takes". During the 1918 Flu pandemic, there was no vaccine, and we went with the "herd immunity" paradigm similar to what is now advocated by Atlas. 50 million people died, at a time when the population of the United States was about 100 million. That, in a nutshell, is why it is so important to follow Dr. Fauci's advice now, until we have the vaccine available and in use. Totally agree with your last sentence. To clarify: 50 million people died worldwide with 675,000 deaths in the US.
|
|
|
Post by hcpride on Nov 16, 2020 13:59:41 GMT -5
WH's supposed Corona expert, Dr. Scott Atlas, criticized Michigan Governor Whitmer's steps to control the virus and advised Michiganders' to "rise up" against her protocols (whatever that means). Dr. Fauci, it turn, stated that "he totally disagrees with the stand that he (Atlas) takes". During the 1918 Flu pandemic, there was no vaccine, and we went with the "herd immunity" paradigm similar to what is now advocated by Atlas. 50 million people died, at a time when the population of the United States was about 100 million. That, in a nutshell, is why it is so important to follow Dr. Fauci's advice now, until we have the vaccine available and in use. On thing that strikes many researchers of the 1918 pandemic is the enormous toll it took on young and healthy US soldiers. About 45,000 US soldiers died. This particular virus (Covid), in stark contrast, has infected 56,000 US servicepersons but killed just 8 (none younger than age 33...and 3 aged 55 or older). www.airforcemag.com/snapshot-dod-and-covid-19/
|
|
|
Post by ndgradbuthcfan on Nov 16, 2020 14:42:25 GMT -5
At first blush, that seems unbelievable. But not so much when one realizes that in 1918 the average US life expectancy for women was 42.2 and men 36.2!
|
|
|
Post by CHC8485 on Nov 16, 2020 16:06:41 GMT -5
That and there was no such thing as antibiotics to treat the respiratory infections that can result from the flu and that many of those US soldiers were just back from or maybe still fighting in the trenches of Europe where, I'm sure their immune systems were not exactly functioning optimally - even by 1918 standards.
Other than being in the Army and 20-something years old, not a whole lot of similarities.
|
|
|
Post by hcpride on Nov 16, 2020 16:15:09 GMT -5
That and there was no such thing as antibiotics to treat the respiratory infections that can result from the flu and that many of those US soldiers were just back from or maybe still fighting in the trenches of Europe where, I'm sure their immune systems were not exactly functioning optimally - even by 1918 standards. Other than being in the Army and 20-something years old, not a whole lot of similarities. The vast difference between 45,000 (Spanish Flu) and 8 (Covid) US military deaths might be explained by many factors (medicine, immune systems, etc.) and the most obvious is that Covid is simply not a deadly threat to the current population/age group in the US Military. (BTW, not one 20-something-year-old in the ranks has died of Covid, and the number of infected must be far more than the confirmed 56,000 given the military's very limited testing and rather close living/working/exercising quarters)
|
|
|
Post by KY Crusader 75 on Nov 16, 2020 16:21:42 GMT -5
At first blush, that seems unbelievable. But not so much when one realizes that in 1918 the average US life expectancy for women was 42.2 and men 36.2! I wonder if that low life expectancy was due more to many people dying as infants rather than to people dying in their 40's & 50's? My father was the last of 7 children born maybe 1898 to 1914 with 3 dying as infants. My mother was one of 9 born 1910 to 1925 and none died before age 65 with most reaching 80.
|
|